APLICACIÓN EN LA AGROINDUSTRIA Y EL ÁREA MÉDICA

PROBLEMA/OPORTUNIDAD

  • Necesidad de materiales que minimicen el impacto ambiental en la agricultura.
  • Necesidad de materiales que contribuyan a la sustentabilidad y a la mejora de envases y embalajes.
  • Vulnerabilidad de la población frente a riesgos de desastres de origen natural y antrópico.

EXPERIENCIA PREVIA

  • Desarrollo de envases y embalajes en base biopolímeros, con prestaciones similares a la de los plásticos sintéticos.
  • Generación de soluciones innovadoras y atingentes al sector agrícola en base a polímeros compostables.
  • Utilización con fines medicinales de la rica reserva vegetal autóctona de nuestro país.

PROYECTOS EN EJECUCIÓN

  • Desarrollo de una formulación en base a polímero biomimético para aminorar el daño por heladas en la fruticultura (2020-2022).

FONDEF IDEA EN DOS ETAPAS – CONICYT. Director: Saddys Rodríguez.

  • Implementación de soluciones tecnológicas para la valorización de la vinicultura en el Valle del Itata (2018-2021).

Fortalecimiento PYMES, Programa Regional – CONICYT. Director: Saddys Rodríguez.

  • Donut-shaped starch microparticles: preparation, characterization and applications (2019- 2022).

FONDECYT Regular – CONICYT. Investigador Principal: Saddys Rodríguez.

  • Development of new microbial resistances self-decontaminating fabrics from biopolymers encapsulated metal-oxide nanocomposite and nylon fabrics for textile (defence) applications (2019-2022).

FONDECYT Postdoctorado – CONICYT. Investigador Principal: Karthikeyan Chandrasekaran.

  • Espectrómetro de Masas por Plasma Acoplado Inductivamente integrado a Cromatógrafo Iónico (IC-ICP/MS), con impacto real en las regiones del sur de Chile (2019-2021).

FONDEQUIP – CONICYT. Investigador Principal: Mónica Pérez; co-investigadora: Saddys Rodríguez.

  • Polymer nano/microparticles as carriers of bioactive compunds. (2019-2022).

Apoyo a la Formación de Redes Internacionales – CONICYT. Director: Saddys Rodríguez.

PUBLICACIONES DESTACADAS (ÚLTIMOS 5 AÑOS)

  • Kokkarachedu, Varaprasad; Tippabattini Jayaramudu*; Gownolla Malegowd Raghavendra; Gangireddygari Venkata Subba Reddy; A. Babul Reddy; K. Sudhakar; Emmanuel Rotimi Sadiku. Preparation and characterization of poly(ethylene glycol) stabilized nano silver particles by a mechanochemical assisted ball mill process. Journal of Applied Polymer Science 133 (2016).
  • Kokkarachedu, Varaprasad*; Gownolla Malegowd Raghavendrab; Tippabattini Jayaramuduc; Jongchul Seob. Nano zinc oxide–sodium alginate antibacterial cellulose fibres. Carbohydrate Polymers 135 (2016).
  • Kokkarachedu, Varaprasad*; Jayaramudu, T*., Raghavendra, G. M., Varaprasad, K., Raju, K. M., Sadiku, E. R. and Kim. 5-Fluorouracil encapsulated magnetic nanohydrogels for drug-delivery applications. Journal of Applied Polymer Science 133 (2016).
  • Kokkarachedu, Varaprasad; G. M. Raghavendra, J. Jung, D. kim, K. Varaprasad, J. Seo*. Identification of silver cubic structures during ultrasonication of chitosan AgNO3 solution. Carbohydrate Polymers 152 (2016).
  • Rodríguez, Saddys*; Rojas, Claudio; Lightfoot, Sarah; Pérez, Mónica; Bouza, Rebeca; Haensgen, Astrid; González, Marcelo. Synthesis and characterization of polyhydroxybutyrate-co-hydroxyvalerate nanoparticles for encapsulation of quercetin. Journal of Bioactive and Compatible Polymers (2016).
  • Rodríguez, Saddys; Rojas, Claudio; Daza, Carla; Smith, Carlos; Mondaca, María*; Campos, Victor. Reducción de selenito a Selenio elemental por Pantoea agglomerans. Gayana 80 (2016).
  • Rodríguez, Saddys; M. Rico*, L. Barral, R. Bouza, B. Montero. Processing and characterization of polyols plasticized-starch reinforced with microcrystalline cellulose. Carbohydrate Polymers 149 (2016).
  • Rodríguez, Saddys; Miranda, Cristian*; Castaño, Johanna; Mondaca, María. Cu nanoparticles/PVC composites: Thermal, rheological and antibacterial properties. Advances in Polymer Technology (2016).
  • Kokkarachedu, Varaprasad*; Manuel Pariguana, G. M.Raghavendrac, T. Jayaramudud, E. R. Sadikue, Development of biodegradable metaloxide/polymer nanocomposite films based on poly-ε-caprolactone and terephthalic acid. Materials Science and Engineering C 70 (2017).
  • Kokkarachedu, Varaprasad*; K. Ramama*, B.S. Diwakar*, V. Swaminadham. V. Reddy, Magnetic properties of nano-multiferroic materials. Journal of Magnetism and Magnetic Materials 442 (2017).
  • Kokkarachedu, Varaprasad*; T. Jayaramudu, R. Sadiku; Removal of dye by carboxymethyl cellulose, acrylamide and graphene oxide via a free radical polymerization process. Journal Carbohydrate Polymers 164 (2017).
  • Kokkarachedu, Varaprasad; T. Jayaramudu, Emmanuel Rotimi Sadiku, Hyun Chan Kim, Jaehwan Kim*, Preparation of antibacterial temperature-sensitive silver-nanocomposite hydrogels from N-isopropylacrylamide with green tea. Journal of Applied Polymer Science 134 (2017)
  • Kokkarachedu, Varaprasad; Bhagavathula* S Diwakara, David Quezada Acunaa, Koduri Ramama*, Veluri Swaminadhamd, Venu Reddy; Insight of electrical behavior in ferroelectricsemiconductor polymer nanocomposite films of PVDF/ZnSe and PVDF/Cu:ZnSe. Journal of Applied Polymer Science 134 (2017).
  • Kokkarachedu, Varaprasad; Tippabattini Jayaramudu, Hyun Chan Kim, Abdullahil Kafy, Jung Woong Kim*, Jaehwan Kim. Calcinated tea and cellulose composite films and its dielectric and lead adsorption properties. Journal Materials Science and Engineering C 171 (2017).
  • Kokkarachedu, Varaprasad*; G. M. Raghavendra, T. Jayaramudu, M. M. Yallapu, S.Rotimi. A mini review on hydrogels classification and recent developments in miscellaneous applications. Journal Materials Science and Engineering C (2017).
  • Kokkarachedu, Varaprasad*; Bhagavathula S Diwakar, Cristina Donoso, Koduri Ramam, Rotimi Sadiku. Metal-oxide polymer nanocomposite films from disposable scrap tire powder/poly- ε-caprolactone for advanced electrical energy (capacitor) applications. Journal of Cleaner Production (2017).
  • Kokkarachedu, Varaprasad*; T. Jayaramudu*, G.M. Raghavendra, E.R Sadiku, K. Mohana Raju. Green synthesis of tea Ag nanocomposite hydrogels via mint leaf extraction for effective antibacterial activity. Journal of Biomaterials Science, Polymer Edition (2017).
  • Kokkarachedu, Varaprasad; T. Prabhakaran*, R.V. Mangalaraja*, Juliano C. Denardin, R. Udayabhaskar, H.D. Mansilla, David Contreras. Studies on the functional properties of freestanding polyvinyl alcohol/(CoFe2O4/CoFe2) composite films. Journal Materials Science and Engineering C 266 (2017).
  • S. Rodríguez-Llamazares, B. Montero*, M. Rico, L. Barral, L., R. Bouza, Effect of nanocellulose as a filler on biodegradable thermoplastic starch films from tuber, cereal and legume. Journal Carbohydrate Polymers 157 (2017).
  • S. Rodríguez-Llamazares*, E. Sepúlveda, C. Pozo, J. Castaño, D. Giraldo, R. Bouza, Morphological and structural changes of starch during processing by melt blending. STARCH-STARKE 69 (2017).
  • S. Rodríguez-Llamazares, I. Restrepo*, N. Benito, C. Medina, R. V. Mangalaraja, P. Flores, Development and characterization of polyvinyl alcohol stabilized polylactic acid/ZnO nanocomposites. Journal Materiales  Research Express (2017).
  • Kokkarachedu, Varaprasad*, Co-assembled ZnO (shell) – CuO (core) nano-oxide materials for microbial protection. Journal Phosphorus, Sulfur, and Silicon and the Related Elements. Vol. 193 (2018).
  • Rodríguez-Llamazares, Saddys; Ide, Walther; Farrag, Yousof; Montero, Belén; Rico, Maite; Barral, Luis; Bouza, Rebeca*; Preparation of starch nanoparticles loaded with quercetin using nanoprecipitation technique. International Journal of Biological Macromolecules. Vol. 114 (2018).
  • Kokkarachedu, Varaprasad*; Nuñez, Dariela*; Elgueta, Elizabeth; Yallapu, Murali Mohan; Jayaramudu, Tippabattini; Oyarzun, Patricio; Nano-hydroxyapatite polymeric hydrogels for dye removal. RSC Advances. Vol. 32 (2018).
  • Kokkarachedu, Varaprasad; Prabhakaran, Thandapani*; Mangalaraja, Ramalinga; Denardin, Juliano; The effect of capping agents on the structural and magnetic properties of cobalt ferrite nanoparticles. Journal of Materials Science: Materials in Electronics. Vol. 29 (2018).
  • Rodríguez-Llamazares, Saddys*; Sabando, Constanza; Farrag, Yousof; Barral, Luis; Bouza, Rebeca; Rojas, Claudio. Preparation of donut-shaped starch microparticles by aqueousalcoholic treatment. Journal Food Chemistry. Vol. 246 (2018).
  • Rodríguez-Llamazares, Saddys*; Restrepo, Iván; Medina, Carlos; Meruane, Viviana; AkbariFakhrabadi, Ali; Flores, Paulo*. The effect of molecular weight and hydrolysis degree of poly(vinyl alcohol)(PVA) on the thermal and mechanical properties of poly(lactic acid)/PVA blends. Polímeros ciencia e tecnología. Vol. 28 (2018).
  • Rodríguez-Llamazares, Saddys; Ide, Walther; Farrag, Yousof; Montero, Belén; Rico, Maite; Barral, Luis; Bouza, Rebeca*. Starch films loaded with donut-shaped starch-quercetin microparticles: Characterization and release kinetics. International Journal of Biological Macromolecules. Vol. 118 (2018).
  • Rodríguez-Llamazares, Saddys; Restrepo, Iván; Flores, Paulo*. Antibacterial Nanocomposite of Poly(Lactic Acid) and ZnO Nanoparticles Stabilized with Poly(Vinyl Alcohol): Thermal and Morphological Characterization. Journal Polymer-Plastics Technology and Engineering. Publicado on-line (2018).
  • Rodríguez-Llamazares, Saddys; Farrag, Yousof; Malmir, Sara; Rico, Maite; Barral, Luis; Bouza, Rebeca*. Starch edible films loaded with donut-shaped starch microparticles. Journal WTFood Science and Technology. Vol. 98 (2018).
  • Rodríguez-Llamazares, Saddys*; Pozo, Claudio*; Bouza, Rebeca; Cataño, Johanna, Müller, Niels; Restrepo, Iván. Study of the structural order of native starch granules using combined FTIR and XRD analysis. Journal of Polymer Research. Publicado on-line (2018).
  • Saddys Rodríguez-Llamazares, Natalia Pettinelli, Vanessa Abella, Luis Barral, Rebeca Bouza, Yousof Farrag, Francisca Lago, Entrapment of chitosan, pectin or κ-carrageenan within methacrylate based hydrogels: Effect on swelling and mechanical properties. Materials Science & Engineering C. Vol. 96 (2019).
  • Kokkarachedu Varaprasad, T Jayaramudua, Radha D. Pyarasanic, K. Koteshwara reddy, Kanderi Dileep Kumar, A. Akbari-Fakhrabadie, R.V. Mangalaraja, John Amalraja, Chitosan capped copper oxide/copper nanoparticles encapsulated microbial resistant nanocomposite films. International Journal of Biological Macromolecules (2019).
  • Kokkarachedu Varaprasad, Dariela Núñez, Murali Mohan Yallapu, Patricio Oyarzún, Matías López, T. Jayaramudu, Chandrasekaran Karthikeyan, Generation of engineered core-shell antibiotic nanoparticles. RSC Advances. Vol. 9 (2019).
  • Kokkarachedu Varaprasad, T Jayaramudua, Rotimi,S, John Amalraja, Temperature-sensitive semi-IPN composite hydrogels for antibacterial applications. Colloids and Surfaces A: Physicochemical and Engineering Aspects. Vol. 572. (2019).
  • Kokkarachedu Varaprasad, T. Prabhakaran, R. Udayabhaskar, R.V. Mangalaraja, Saeed Farhang Sahlevani, Rafael M Freire, Juliano C Denardin, F. Béron, KMiguel Angel GraciaPinilla, Marcus Vinicius-Araújo, Andris F Bakuzis, Probing the Defect Induced Magnetocaloric Effect on Ferrite/Graphene Functional Nanocomposites and their Magnetic Hyperthermia. ACS, The Journal of Physical Chemistry C. Vol. 123 (2019).
  • Chandrasekaran Karthikeyan, Kokkarachedu Varaprasad, V. Senthil Kumar, L. Arun, A.S Haja Hameed, Synergistic antibacterial effect of the Magnesium doped ZnO nanoparticles with Chloramphenicol. BioNanoScience (2019).
  • Karthikeyan, C., Varaprasad, K., Akbari-Fakhrabadi, A., Hameed, A.S.H., Sadiku, R. Biomolecule chitosan, curcumin and ZnO-based antibacterial nanomaterial, via a one-pot process. Carbohydrate Polymers (2020).
  • Sabando, C., Rodríguez-Díaz, M., Ide, W., Pastene, E., Avello, M., Simirgiotis, M., Rojas, S., Villarroel, E., Silva-Grecchi, T., Gutiérrez, C., Bouza, R., Cicchelli, B., González, M., Rodríguez-Llamazares, S. Improvement of endothelial function by Gunnera tinctoria extract with antioxidant properties. Biological Research (2020).
  • Pettinelli, N., Rodríguez-Llamazares, S., Bouza, R., Barral, L., Feijoo-Bandín, S., Lago, F. Carrageenan-based physically crosslinked injectable hydrogel for wound healing and tissue repairing applications. International Journal of Pharmaceutics (2020).
  • Kanikireddy, V., Varaprasad, K., Rani, M.S., Venkataswamy, P., Mohan Reddy, B.J., Vithal, M. Biosynthesis of CMC-Guar gum-Ag0 nanocomposites for inactivation of food pathogenic microbes and its effect on the shelf life of strawberries. Carbohydrate Polymers (2020).
  • Varaprasad, K., Jayaramudu, T., Kanikireddy, V., Toro, C., Sadiku, E.R. Alginate-based composite materials for wound dressing application:A mini review. Carbohydrate Polymers (2020).
  • Varaprasad, K., López, M., Núñez, D., Jayaramudu, T., Sadiku, E.R., Karthikeyan, C., Oyarzún, P. Antibiotic copper oxide-curcumin nanomaterials for antibacterial applications. Journal of Molecular Liquids (2020).
  • Pettinelli, N., Rodríguez-Llamazares, S., Farrag, Y., Bouza, R., Barral, L., Feijoo-Bandín, S., Lago, F. Poly(hydroxybutyrate-co-hydroxyvalerate) microparticles embedded in κ-carrageenan/ locust bean gum hydrogel as a dual drug delivery carrier. International Journal of Biological Macromolecules (2020).
  • Varaprasad, K., Núñez, D., Ide, W., Jayaramudu, T., Sadiku, E.R. Development of high alginate comprised hydrogels for removal of Pb(II) ions. Journal of Molecular Liquids (2020).
  • Valenzuela-Villar, M., Bastías, R.M., Rodriguez, S., Sabando, C. Pva polymer as a tool to prevent frost damage on cherry prunus Avium L. Flower. Chilean Journal of Agricultural and Animal Sciences (2020).
  • Sabando, C., Ide, W., Rodríguez-Díaz, M., Cabrera-Barjas, G., Castaño, J., Bouza, R., Müller, N., Gutiérrez, C., Barral, L., Rojas, J., Martínez, F., Rodríguez-Llamazares, S. A novel hydrocolloid film based on pectin, starch and gunnera tinctoria and ugni molinae plant extracts for wound dressing applications. Current Topics in Medicinal Chemistry (2020).